ESPCI Paris – PSL Research University | CNRS Flagship Grant | Paris, France

DNA is not just the blueprint of life – it is emerging as the ultimate medium for data storage and computation. With its unparalleled information density and stability, DNA can encode entire digital universes – texts, images, videos – within a few microliters of solution. While DNA data storage has seen rapid progress, the next frontier lies in computing directly on massive DNA-encoded databases: querying, filtering, searching, encrypting, and compressing information in molecular form.

At ESPCI Paris (PSL), supported by a prestigious CNRS flagship research grant, our team is pioneering this frontier. We are looking for a talented and ambitious postdoctoral researcher to help design the next generation of DNA-based computers – systems capable of handling and manipulating information in unprecedented ways.

🔬 The Project

You will work at the crossroads of molecular programming, synthetic biology, microfluidics, and computer science, developing sophisticated biochemical circuits able to answer non-trivial queries directly from DNA databases (e.g., “What is the shortest path between node X and node Y?”).

Building on our laboratory’s strong expertise in DNA-programmed systems and enzyme-driven molecular circuits, you will create experimental implementations of algorithms encoded in the language of life itself.

🌍 What We Offer

  • A fully funded postdoctoral position at one of France’s most prestigious institutions.
  • A stimulating, international research environment in the heart of Paris.
  • Close collaborations with leading experts in France and Japan.
  • Opportunities to publish in high-impact journals and present at international conferences.
  • A chance to shape the future of molecular information technologies.

👩‍🔬 We are looking for

a motivated, creative researcher or student ready to push the boundaries of molecular computation:

➕More

📄 For publications and further insight into our work: https://blog.espci.fr/guillaumegines/publications/

✨ Join us in redefining the future of computation – not with silicon, but with DNA.

Send CV and brief cover letter to guillaume.gines[at]espci.fr