Pezet Sophie

Pezet Sophie

Associate professor at ESPCI Paris
sophie.pezet@espci.fr
See ResearchGate profile >

Education

  • 2009 – “Habilitation à Diriger des Recherches”, Université Paris VI, France
  • 2005 – Qualification for applying to an associate professor position in sections 65 (CellularBiology) and 69 (Neurosciences) of the French CNU.
  • 1999 – PhD in Neurosciences, Université Paris XII, Créteil, France
    “Implication of the Nerve Growth Factor in the neuronal plasticity processes underlying chronic pain states in a model for inflammatory pain: Freund adjuvant-induced arthritis in rat.”
  • 1995-1996 – Master of Science in Neurosciences, Université Paris VI, France

Professional experience

  • 1996-1999 – PhD Neuroscience laboratory INSERM U421, Creteil.
  • 2000-2002 – Postdoctoral fellow at King’s College London, UK. Laboratory of Prof. SB McMahon.
  • 2003-2007 – Postdoctoral fellow among the London Paris consortium (King’s College London and University London).
  • 2008 – 2017- Researcher at the laboratory ‘Brain plasticity, CNRS UMR 8249, ESPCI
  • Since 2018 – Researcher at the laboratory ‘Physics for Medicine’, INSERM, CNRS, ESPCI
  • since 2008 – Tenured lecturer in Physiology at ESPCI Paris, France

Activities and Responsabilities

  • 2007- Now – Co-responsible of the practicals of Physiology at ESPCI, Paris
  • 2015-2018 – Deputy dean for academic affaires at ESPCI Paris, France
  • 2014-now – Co-director of the module ‘Drugs and pathologies’ at the PSL week.
  • Since 2010 – Member of the ethic committee CEEA59.
  • 2010-2017 – Head of the animal facility of the laboratory ‘Brain Plasticity, ESPCI, Paris’.
  • 2018-2023 – Head of the animal facility at the laboratory ‘Physics for Medicine’, Paris.

Publications and citations

  • Orcid number : 0000-0002-3305-3315
  • Total number of publications in peer-reviewed journals : 58
  • Total number of citations: 5779
  • H index : 35

Research topics

  • Brain plasticity
  • Sensory disorders
  • Migraine
  • Behavioural studies

Main publications

1
Pezet S, McMahon SB. NEUROTROPHINS: Mediators and Modulators of Pain. Annu Rev Neurosci 2006;29:507–38. https://doi.org/10.1146/annurev.neuro.29.051605.112929.
1
Thibault K, Calvino B, Pezetl S. Characterisation of sensory abnormalities observed in an animal model of multiple sclerosis: A behavioural and pharmacological study. European Journal of Pain 2011;15:231.e1-231.e16. https://doi.org/10.1016/j.ejpain.2010.07.010.
1
Thibault K, Calvino B, Dubacq S, Roualle-de-Rouville M, Sordoillet V, Rivals I, et al. Cortical effect of oxaliplatin associated with sustained neuropathic pain: Exacerbation of cortical activity and down-regulation of potassium channel expression in somatosensory cortex. Pain 2012;153:1636–47. https://doi.org/10.1016/j.pain.2012.04.016.
1
Thibault K, Lin WK, Rancillac A, Fan M, Snollaerts T, Sordoillet V, et al. BDNF-Dependent Plasticity Induced by Peripheral Inflammation in the Primary Sensory and the Cingulate Cortex Triggers Cold Allodynia and Reveals a Major Role for Endogenous BDNF As a Tuner of the Affective Aspect of Pain. J Neurosci 2014;34:14739–51. https://doi.org/10.1523/JNEUROSCI.0860-14.2014.

Latest publications

1
Koorliyil H, Sitt J, Rivals I, Liu Y, Bertolo A, Cazzanelli S, et al. Specific and non-uniform brain states during cold perception in mice. J Neurosci 2024:e0909232023. https://doi.org/10.1523/JNEUROSCI.0909-23.2023.
1
Renaudin N, Pezet S, Ialy-Radio N, Demene C, Tanter M. Backscattering amplitude in ultrasound localization microscopy. Scientific Reports 2023;13:. https://doi.org/10.1038/s41598-023-38531-w.
1
Renaudin N, Tanter M, Pezet S. L’imagerie fonctionnelle ultrasonore à résolution microscopique. Société Des Neurosciences 2023;64:.
1
Nouhoum M, Ferrier J, Osmanski B-F, Ialy-Radio N, Pezet S, Tanter M, et al. A functional ultrasound brain GPS for automatic vascular-based neuronavigation. Sci Rep 2021;11:15197. https://doi.org/10.1038/s41598-021-94764-7.
1
Tiran E, Ferrier J, Deffieux T, Gennisson J-L, Pezet S, Lenkei Z, et al. Transcranial Functional Ultrasound Imaging in Freely Moving Awake Mice and Anesthetized Young Rats without Contrast Agent. Ultrasound in Medicine & Biology 2017;43:1679–89. https://doi.org/10.1016/j.ultrasmedbio.2017.03.011.
1
Gautier A, El Ouaraki H, Bazin N, Salam S, Vodjdani G, Bourgoin S, et al. Lentiviral vector-driven inhibition of 5-HT synthesis in B3 bulbo-spinal serotonergic projections – Consequences on nociception, inflammatory and neuropathic pain in rats. Experimental Neurology 2017;288:11–24. https://doi.org/10.1016/j.expneurol.2016.10.016.
1
Thibault K, Rivière S, Lenkei Z, Férézou I, Pezet S. Orofacial Neuropathic Pain Leads to a Hyporesponsive Barrel Cortex with Enhanced Structural Synaptic Plasticity. PLoS ONE 2016;11:e0160786. https://doi.org/10.1371/journal.pone.0160786.
1
Errico C, Osmanski B-F, Pezet S, Couture O, Lenkei Z, Tanter M. Transcranial functional ultrasound imaging of the brain using microbubble-enhanced ultrasensitive Doppler. NeuroImage 2016;124:752–61. https://doi.org/10.1016/j.neuroimage.2015.09.037.
1
Errico C, Pierre J, Pezet S, Desailly Y, Lenkei Z, Couture O, et al. Ultrafast ultrasound localization microscopy for deep super-resolution vascular imaging. Nature 2015;527:499–502. https://doi.org/10.1038/nature16066.
1
Osmanski B-F, Pezet S, Ricobaraza A, Lenkei Z, Tanter M. Functional ultrasound imaging of intrinsic connectivity in the living rat brain with high spatiotemporal resolution. Nat Commun 2014;5:5023. https://doi.org/10.1038/ncomms6023.