Demené Charlie

Demené Charlie

Associate professor at ESPCI Paris
charlie.demene@espci.fr
See ResearchGate profile >

Education

  • 2015 – PhD in Physics, Université Paris Diderot, France
    “Vascular and functional brain mapping via Ultrafast Doppler imaging: applications to preclinical and neonate cerebral imaging”
  • 2010 – Master of Science in Signal, Image and Shape recognition, Telecom ParisTech, France
  • 2010 – Engineering degree at ESPCI Paris (Ecole Supérieure de Physique et de Chimie Industrielles), France

Professional experience

  • since 2017 – Associate professor in Acoustics at ESPCI Paris, France
  • 2016-2017 – Postdoctoral researcher at University Hospital Geneva, Switzerland/Institut Langevin Ondes et Images, France
  • 2010-2011 – R&D engineer at Echosens, Paris, France

Main awards and distinctions

  • Prize of the Chancellerie des Universités de Paris in 2016
  • Best Student Paper Award of the IEEE International Ultrasonics Symposium in 2014, Chicago, USA
  • Best Student Award at the 18th Meeting of the European Society of Neurosonology and Cerebral Hemodynamics in 2013, Porto, Portugal

Research topics

  • ultrasensitive Doppler imaging
  • functional ultrasound imaging
  • ultrafast ultrasound imaging of the brain

Main publications

1
Renaudin N, Demené C, Dizeux A, Ialy-Radio N, Pezet S, Tanter M. Functional ultrasound localization microscopy reveals brain-wide neurovascular activity on a microscopic scale. Nat Methods 2022;19:1004–12. https://doi.org/10.1038/s41592-022-01549-5.
1
Baranger J, Demené C, Frerot A, Faure F, Delanoë C, Serroune H, et al. Bedside functional monitoring of the dynamic brain connectivity in human neonates. Nature Communications 2021;12:1080. https://doi.org/10.1038/s41467-021-21387-x.
1
Demené C, Robin J, Dizeux A, Heiles B, Pernot M, Tanter M, et al. Transcranial ultrafast ultrasound localization microscopy of brain vasculature in patients. Nat Biomed Eng 2021;5:219–28. https://doi.org/10.1038/s41551-021-00697-x.
1
Demené C, Mairesse J, Baranger J, Tanter M, Baud O. Ultrafast Doppler for neonatal brain imaging. NeuroImage 2019;185:851–6. https://doi.org/10.1016/j.neuroimage.2018.04.016.
1
Demené C, Deffieux T, Pernot M, Osmanski B-F, Biran V, Gennisson J-L, et al. Spatiotemporal Clutter Filtering of Ultrafast Ultrasound Data Highly Increases Doppler and fUltrasound Sensitivity. IEEE Trans Med Imaging 2015;34:2271–85. https://doi.org/10.1109/TMI.2015.2428634.

Latest publications

1
Faure F, Baranger J, Alison M, Boutillier B, Frérot A, Lim C, et al. Quantification of brain-wide vascular resistivity via ultrafast Doppler in human neonates helps early detection of white matter injury. J Cereb Blood Flow Metab 2024:0271678X241232197. https://doi.org/10.1177/0271678X241232197.
1
Cadoni S, Demené C, Alcala I, Provansal M, Nguyen D, Nelidova D, et al. Ectopic expression of a mechanosensitive channel confers spatiotemporal resolution to ultrasound stimulations of neurons for visual restoration. Nat Nanotechnol 2023. https://doi.org/10.1038/s41565-023-01359-6.
1
Robin J, Demené C, Heiles B, Blanvillain V, Puke L, Perren F, et al. In vivo adaptive focusing for clinical contrast-enhanced transcranial ultrasound imaging in human. Phys Med Biol 2023;68:25019. https://doi.org/10.1088/1361-6560/acabfb.
1
Demené C, Baranger J, Bernal M, Delanoe C, Auvin S, Biran V, et al. Functional ultrasound imaging of brain activity in human newborns. Sci Transl Med 2017;9:eaah6756. https://doi.org/10.1126/scitranslmed.aah6756.