Demené Charlie

Demené Charlie

Associate professor at ESPCI Paris
charlie.demene@espci.fr
See ResearchGate profile >

Education

  • 2015 – PhD in Physics, Université Paris Diderot, France
    “Vascular and functional brain mapping via Ultrafast Doppler imaging: applications to preclinical and neonate cerebral imaging”
  • 2010 – Master of Science in Signal, Image and Shape recognition, Telecom ParisTech, France
  • 2010 – Engineering degree at ESPCI Paris (Ecole Supérieure de Physique et de Chimie Industrielles), France

Professional experience

  • since 2017 – Associate professor in Acoustics at ESPCI Paris, France
  • 2016-2017 – Postdoctoral researcher at University Hospital Geneva, Switzerland/Institut Langevin Ondes et Images, France
  • 2010-2011 – R&D engineer at Echosens, Paris, France

Main awards and distinctions

  • Prize of the Chancellerie des Universités de Paris in 2016
  • Best Student Paper Award of the IEEE International Ultrasonics Symposium in 2014, Chicago, USA
  • Best Student Award at the 18th Meeting of the European Society of Neurosonology and Cerebral Hemodynamics in 2013, Porto, Portugal

Research topics

  • ultrasensitive Doppler imaging
  • functional ultrasound imaging
  • ultrafast ultrasound imaging of the brain

Main publications

1
Renaudin N, Demené C, Dizeux A, Ialy-Radio N, Pezet S, Tanter M. Functional ultrasound localization microscopy reveals brain-wide neurovascular activity on a microscopic scale. Nat Methods 2022;19:1004–12. https://doi.org/10.1038/s41592-022-01549-5.
1
Baranger J, Demené C, Frerot A, Faure F, Delanoë C, Serroune H, et al. Bedside functional monitoring of the dynamic brain connectivity in human neonates. Nature Communications 2021;12:1080. https://doi.org/10.1038/s41467-021-21387-x.
1
Demené C, Robin J, Dizeux A, Heiles B, Pernot M, Tanter M, et al. Transcranial ultrafast ultrasound localization microscopy of brain vasculature in patients. Nat Biomed Eng 2021;5:219–28. https://doi.org/10.1038/s41551-021-00697-x.
1
Demené C, Mairesse J, Baranger J, Tanter M, Baud O. Ultrafast Doppler for neonatal brain imaging. NeuroImage 2019;185:851–6. https://doi.org/10.1016/j.neuroimage.2018.04.016.
1
Demené C, Deffieux T, Pernot M, Osmanski B-F, Biran V, Gennisson J-L, et al. Spatiotemporal Clutter Filtering of Ultrafast Ultrasound Data Highly Increases Doppler and fUltrasound Sensitivity. IEEE Trans Med Imaging 2015;34:2271–85. https://doi.org/10.1109/TMI.2015.2428634.

Latest publications

1
Faure F, Uchitel J, De Crescenzo S, Edwards A, Baranger J, Pammenter K, et al. Cot-side functional imaging in neonates for early neurodevelopment monitoring using functional ultrasound (fUS) connectivity imaging and the combination of fUS with diffuse optical tomography (fUS-DOT): A feasibility study. Developmental Cognitive Neuroscience 2026;77:. https://doi.org/10.1016/j.dcn.2025.101652.
1
Morin C, Faure F, Mollet J, Guenoun D, Heydari-Olya A, Sautet I, et al. C-section and systemic inflammation synergize to disrupt the neonatal gut microbiota and brain development in a model of prematurity. Brain Behavior and Immunity 2025;123:824–37. https://doi.org/10.1016/j.bbi.2024.10.023.
1
Zucker N, Le Meur-Diebolt S, Cybis Pereira F, Baranger J, Hurvitz I, Demené C, et al. Physio-fUS: a tissue-motion based method for heart and breathing rate assessment in neurofunctional ultrasound imaging. eBioMedicine 2025;112:105581. https://doi.org/10.1016/j.ebiom.2025.105581.
1
Zamfirov L, Nguyen N-M, Fernández-Sánchez ME, Cambronera Ghiglione P, Teston E, Dizeux A, et al. Acoustic-pressure-driven ultrasonic activation of the mechanosensitive receptor RET and of cell proliferation in colonic tissue. Nat Biomed Eng 2024:1–12. https://doi.org/10.1038/s41551-024-01300-9.
Nov 21, 2022 | |
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