Demené Charlie

Demené Charlie

Associate professor at ESPCI Paris
charlie.demene@espci.fr
See ResearchGate profile >

Education

  • 2015 – PhD in Physics, Université Paris Diderot, France
    “Vascular and functional brain mapping via Ultrafast Doppler imaging: applications to preclinical and neonate cerebral imaging”
  • 2010 – Master of Science in Signal, Image and Shape recognition, Telecom ParisTech, France
  • 2010 – Engineering degree at ESPCI Paris (Ecole Supérieure de Physique et de Chimie Industrielles), France

Professional experience

  • since 2017 – Associate professor in Acoustics at ESPCI Paris, France
  • 2016-2017 – Postdoctoral researcher at University Hospital Geneva, Switzerland/Institut Langevin Ondes et Images, France
  • 2010-2011 – R&D engineer at Echosens, Paris, France

Main awards and distinctions

  • Prize of the Chancellerie des Universités de Paris in 2016
  • Best Student Paper Award of the IEEE International Ultrasonics Symposium in 2014, Chicago, USA
  • Best Student Award at the 18th Meeting of the European Society of Neurosonology and Cerebral Hemodynamics in 2013, Porto, Portugal

Research topics

  • ultrasensitive Doppler imaging
  • functional ultrasound imaging
  • ultrafast ultrasound imaging of the brain

Main publications

1
Renaudin N, Demené C, Dizeux A, Ialy-Radio N, Pezet S, Tanter M. Functional ultrasound localization microscopy reveals brain-wide neurovascular activity on a microscopic scale. Nat Methods 2022;19:1004–12. https://doi.org/10.1038/s41592-022-01549-5.
1
Baranger J, Demené C, Frerot A, Faure F, Delanoë C, Serroune H, et al. Bedside functional monitoring of the dynamic brain connectivity in human neonates. Nature Communications 2021;12:1080. https://doi.org/10.1038/s41467-021-21387-x.
1
Demené C, Robin J, Dizeux A, Heiles B, Pernot M, Tanter M, et al. Transcranial ultrafast ultrasound localization microscopy of brain vasculature in patients. Nat Biomed Eng 2021;5:219–28. https://doi.org/10.1038/s41551-021-00697-x.
1
Demené C, Mairesse J, Baranger J, Tanter M, Baud O. Ultrafast Doppler for neonatal brain imaging. NeuroImage 2019;185:851–6. https://doi.org/10.1016/j.neuroimage.2018.04.016.
1
Demené C, Deffieux T, Pernot M, Osmanski B-F, Biran V, Gennisson J-L, et al. Spatiotemporal Clutter Filtering of Ultrafast Ultrasound Data Highly Increases Doppler and fUltrasound Sensitivity. IEEE Trans Med Imaging 2015;34:2271–85. https://doi.org/10.1109/TMI.2015.2428634.

Latest publications

1
Morin C, Faure F, Mollet J, Guenoun D, Heydari-Olya A, Sautet I, et al. C-section and systemic inflammation synergize to disrupt the neonatal gut microbiota and brain development in a model of prematurity. Brain Behavior and Immunity 2025;123:824–37. https://doi.org/10.1016/j.bbi.2024.10.023.
1
Zucker N, Le Meur-Diebolt S, Cybis Pereira F, Baranger J, Hurvitz I, Demené C, et al. Physio-fUS: a tissue-motion based method for heart and breathing rate assessment in neurofunctional ultrasound imaging. EBioMedicine 2025;112:105581. https://doi.org/10.1016/j.ebiom.2025.105581.
1
Zamfirov L, Nguyen N-M, Fernández-Sánchez ME, Cambronera Ghiglione P, Teston E, Dizeux A, et al. Acoustic-pressure-driven ultrasonic activation of the mechanosensitive receptor RET and of cell proliferation in colonic tissue. Nat Biomed Eng 2024:1–12. https://doi.org/10.1038/s41551-024-01300-9.
1
Faure F, Alison M, Francavilla M, Boizeau P, Guilmin Crepon S, Lim C, et al. Transfontanellar shear wave elastography of the neonatal brain for quantitative evaluation of white matter damage. Sci Rep 2024;14:11827. https://doi.org/10.1038/s41598-024-60968-w.
1
Faure F, Baranger J, Alison M, Boutillier B, Frérot A, Lim C, et al. Quantification of brain-wide vascular resistivity via ultrafast Doppler in human neonates helps early detection of white matter injury. J Cereb Blood Flow Metab 2024:0271678X241232197. https://doi.org/10.1177/0271678X241232197.