Pernot Mathieu

Pernot Mathieu

Director of Physics for Medicine Paris
Research director at Inserm
mathieu.pernot@espci.fr
ResearcherID: G-3404-2013
ORCID: 0000-0001-6713-4642
See the ResearchGate profile >

Education

  • 2015 – “Habilitation à Diriger des Recherches”, Université Paris Diderot, France
  • 2004 – PhD in Physics, Université Paris Diderot, France
    “Ultrasound therapy and monitoring: new techniques”
  • 2001 – Master of Science in Acoustics, Université Paris Diderot, France
  • 2001 – Engineering degree at ESPCI (Ecole Supérieure de Physique et Chimie Industrielles), Paris, France

Professional experience

  • since 2025 – Director of Physics for Medicine Paris (ESPCI-Paris PSL, INSERM, CNRS), Paris, France
  • since 2016 – Tenured research director, Inserm, Paris, France
  • 2019-2024 – Deputy director of Physics for Medicine Paris laboratory, Paris, France
  • 2007-2016 – Tenured research officer, Inserm, Paris, France
  • 2006-2007 – Research Engineer, SuperSonic Imagine, Aix-en-provence, France
  • 2004-2005 – Postdoctoral fellow, Columbia University, New York, USA

Activities and Responsabilities

  • Director of Physics for Medicine Paris institute, Paris, France
  • Co-founder of the company eMyosound
  • Co-founder of the company Iconeus
  • Co-founder of the company Cardiawave
  • Associate Editor of IEEE Transactions of Ultrasonics, Ferroelectrics and Frequency Control
  • Member of the IEEE UFFC Technical Program Committee
  • Member of the International Advisory Board of Physics in Medicine and Biology
  • Editorial advisory panel member: Scientific Reports
  • Co-inventor of more than 40 patents families in the field of biomedical ultrasound
  • Co-author of more than 200 publications in peer-reviewed international journals
  • Citations: 13855, h-index: 65 on Google scholar / Citations: 8810 (h-index: 54) on Web of Science

Main awards and distinctions

  • Prix de la fondation Langlois (2024)
  • Innovator award of Paris – Ile de France (2021)
  • Rotblat Medal, citation prize from Physics in Medicine and Biology (2019)
  • 2016 Outstanding Paper Award of the IEEE Transactions in Ultrasonics, Ferroelectrics and Frequency Control
  • Roberts Prize from the Institute of Physics and Engineering in Medicine (IPEM) (2015)
  • Winner of the BPI ILab Competition for the creation of innovative technology companies in 2014 (project Valvopulse) and 2015 (project Neuroflow)
  • Winner of the Concours Mondial de l’Innovation, phase I, II & III (project Valvosoft)
  • ERC Starting Grant 2012 (project ULTRAECHOCARDIO)

Research topics

  • Biomedical ultrasound
  • Cardiovascular ultrasound imaging
  • Functional ultrasound imaging
  • Ultrafast ultrasound imaging
  • 3D ultrasound imaging
  • Non-invasive ultrasound therapy

Main publications

1
Demeulenaere O, Bertolo A, Pezet S, Ialy-Radio N, Osmanski B, Papadacci C, et al. In vivo whole brain microvascular imaging in mice using transcranial 3D Ultrasound Localization Microscopy. EBioMedicine 2022;79:12. https://doi.org/10.1016/j. ebiom.2022.103995.
1
Demeulenaere O, Sandoval Z, Mateo P, Dizeux A, Villemain O, Gallet R, et al. Coronary Flow Assessment Using 3-Dimensional Ultrafast Ultrasound Localization Microscopy. JACC: Cardiovascular Imaging 2022:16. https://doi.org/10.1016/j.jcmg.2022.02.008.
1
Demené C, Robin J, Dizeux A, Heiles B, Pernot M, Tanter M, et al. Transcranial ultrafast ultrasound localization microscopy of brain vasculature in patients. Nat Biomed Eng 2021;5:219–28. https://doi.org/10.1038/s41551-021-00697-x.
1
Pedreira O, Correia M, Chatelin S, Villemain O, Goudot G, Thiebaut S, et al. Smart ultrasound device for non-invasive real-time myocardial stiffness quantification of the human heart. IEEE Transactions on Biomedical Engineering 2021:1–1. https://doi.org/10.1109/TBME.2021.3087039.
1
Messas E, Rémond MC, Goudot G, Zarka S, Penot R, Mateo P, et al. Feasibility and safety of non-invasive ultrasound therapy (NIUT) on porcine aortic valve. Phys Med Biol 2020. https://doi.org/10.1088/1361-6560/aba6d3.
1
Rabut C, Correia M, Finel V, Pezet S, Pernot M, Deffieux T, et al. 4D functional ultrasound imaging of whole-brain activity in rodents. Nat Methods 2019:1–4. https://doi.org/10.1038/s41592-019-0572-y.
1
Provost J, Garofalakis A, Sourdon J, Bouda D, Berthon B, Viel T, et al. Simultaneous positron emission tomography and ultrafast ultrasound for hybrid molecular, anatomical and functional imaging. NATURE BIOMEDICAL ENGINEERING 2018;2:85–94. https://doi.org/10.1038/s41551-018-0188-z.

Latest publications

1
Venet M, Baranger J, Malik A, Nguyen MB, Mital S, Friedberg MK, et al. Towards non-invasive assessment of myocardial work using myocardial stiffness and strain: a human pilot study. Eur Heart J Cardiovasc Imaging 2025;26:1051–64. https://doi.org/10.1093/ehjci/jeaf089.
1
Leroy H, Wang LZ, Jimenez A, Mohamedi N, Papadacci C, Julia P, et al. Assessment of microvascular flow in human atherosclerotic carotid plaques using ultrasound localization microscopy. EBioMedicine 2025;111:105528. https://doi.org/10.1016/j.ebiom.2024.105528.
1
Trifunović-Zamaklar D, Karan R, Kovačević-Kostić N, Terzić D, Milićević V, Petrović O, et al. Non-Invasive Ultrasound Therapy for Severe Aortic Stenosis: Early Effects on the Valve, Ventricle, and Cardiac Biomarkers (A Case Series). JCM 2024;13:4607. https://doi.org/10.3390/jcm13164607.
1
Goudot G, Jimenez A, Mohamedi N, Sitruk J, Wang LZ, Khider L, et al. Vasa vasorum interna in the carotid wall of active forms of Takayasu arteritis evidenced by ultrasound localization microscopy. Vasc Med 2024:1358863X241228262. https://doi.org/10.1177/1358863X241228262.
1
Khider L, Goudot G, Messas E, Pernot M. Ultrasons dans le traitement des thromboses veineuses. JMV-Journal de Médecine Vasculaire 2024;49:38. https://doi.org/10.1016/j.jdmv.2024.01.078.
1
Baudo M, Magrini E, Pernot M, Sicouri S, Torregrossa G, Beurton A, et al. Hydrophilic polymer embolization after TAVI. Journal of Cardiology 2024;0: https://doi.org/10.1016/j.jjcc.2024.02.008.
Nov 21, 2022 | |
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