About us

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Cyprio is located in the heart of Paris at a major French institute for higher education in science and engineering: the École Supérieure de Physique et de Chimie Industrielles de la Ville de Paris, ESPCI Paris. Emblematic for its world class status, six Nobel Prizes are associated with ESPCI Paris.

Created in 2017, CYPRIO is founded on ten years of research at ESPCI Paris with a strong expertise in the fields of physicochemistry, liver biology and drug screening. This makes Cyprio the holder of a unique technology (BioPearl) for fabrication of spheroids that are physiologically more relevant than traditional monolayer models and are compatible with high throughput screening applications. Our first product, HepatoPearl, has been validated as a beneficial in vitro liver model for different applications from drug-drug interaction screening, chronic toxicity, and metabolism of low clearance compounds to disease modelling. Now Cyprio is developing additional products to definitively change liver cell-culture biology approaches towards more complex and more relevant, yet more robust, easier to handle and HTS compatible 3D cellular models.

The Cyprio Team

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Pr. Jérôme BIBETTE

Professor Jérôme Bibette Director of LCMD, which he founded in 2001 at ESPCI, is world renowned for his research on emulsions, magnetic particles, and colloidal objects. His work in the areas of emulsions, colloid chemistry, complex fluids and soft condensed matter physics led to Silver medal of CNRS. On top of being the author of more than 150 articles and 56 patents, Jérôme is also co-founder of Ademtech, Raindance Technologies, Capsum, HiFi-Bio, BioMillenia, MilliDrop Instruments and iSpheres.

Dr. Gerard Sanderink

Dr Gerard Sanderink is Global Director of the Biomarker and Clinical Bioanalysis Department at Sanofi R&D. After studying Biochemistry and Clinical Biology in Netherlands and in France, he spent his entire career in Sanofi or its predecessor companies, first as laboratory leader in Enzymology of drug metabolism, then in Clinical Pharmacokinetics, before fulfilling several management positions in preclinical and clinical field since 2001.

Dr. Nicolas BREMOND

Dr. Nicolas Bremond Lecturer at the ESPCI since 2010 and a member of the LCMD since 2005, Nicolas Bremond is known for his work in the fields of soft matter and microfluidics, particularly at the interface with cell biology, fluid mechanics and on the physicochemistry of emulsions and liquid atomization. He is the author of 34 articles and 11 patents. He is also co-founder of MilliDrop Instruments and iSpheres.

Dr. Jérôme LARGHERO

Dr. Jérôme Larghero is Professor of cell biology at the Paris Diderot School of Medicine, head of Saint-Louis Hospital Cell Therapy Unit and of the AP-HP Cord Blood Bank. Awarded by the Great Price of the Academy of Science for regenerative medicine and by the Galien Price. Dr. Jérôme Larghero is involved since 20 years in cell-based therapies and stem cell research.

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