This thesis proposal is part of the ANR CarboCHIPS project, which aims to design a direct coupling involving oligo-/polysaccharide- or peptide/protein-based biochips with mass spectrometry (MS)-based approaches.
The introduction of a biochip-MS coupling aims to be able to selectively capture ligands in a complex mixture.
The laboratory has 7 mass spectrometers on site, 2 of which will be particularly used: a MALDI-TOF/TOF and a SELECT SERIES Cyclic IMS ion mobility instrument coupled with a DESI-XS source.