Publications

Non-enzymatic oligonucleotide ligation in coacervate protocells sustains compartment-content coupling
Fraccia, T.P. & Martin, N.
Nature Communications 14, 2606 (2023)

A liquid crystal world for the origin of life
Jia, T.Z.; Bellini, T.; Clark, N.A. & Fraccia, T.P.
Emerging Topics in Life Science 6, 6: 557–569 (2022)

The Pairing Statistics of Random DNA Oligomers: Finding your Partner in Superdiverse Environments
Di Leo, S; Marni, S.; Plata, C.A.; Fraccia, T.P.; Smith, G.P.; Maritan, A.; Suweis, S. & Bellini, T.
PLOS Computational Biology 18, 4, e1010051 (2022)

Liquid – Liquid Crystalline Phase Separation in Biomolecular Solutions
Fraccia, T.P. & Zanchetta, G.
Current Opinion in Colloid & Interface Science 56,101500 (2021)

Liquid Crystal Phase Assembly in Peptide-DNA Coacervates as a Mechanism for Primitive Emergence of Structural Complexity
Jia, T.Z. & Fraccia, T.P.
ALIFE 2021 362, 56 (2021)

Liquid crystal peptide/DNA coacervates in the context of prebiotic molecular evolution
Jia, T.J. & Fraccia, T.P.
Crystals 10, 964, 1-21 (2020)

Liquid Crystal Coacervates Composed of Short Double-Stranded DNA and Cationic Peptides
Fraccia, T.P. & Jia, T.J.
ACS Nano 14, 11, 15071-15082 (2020)

Elasticity and Viscosity of DNA Liquid Crystal
Lucchetti, L.; Fraccia, T.P.; Nava, G; Turiv, T.; Ciciulla, F.; Bethge, L.; Klussmann, S.; Lavrentovich, O. & Bellini, T. 
ACS Macro Letters 9, 7, 1034-1039 (2020)

Liquid Crystal ordering of DNA Dickerson Dodecamer duplexes with different 5’- Phosphate terminations
Todisco, M.; Smith, G.P. & Fraccia, T. P.
Molecular Crystals and Liquid Crystals 683,1, 69-80 (2019)

Phase separations, liquid crystal ordering and molecular partitioning in mixtures of PEG and DNA oligomers
Di Leo, S.; Todisco, M.; Bellini, T. & Fraccia, T. P. 
Liquid Crystals 1-13 (2018)

Nonenzymatic Polymerization into Long Linear RNA Templated by Liquid Crystal Self-Assembly
Todisco, M; Fraccia, T. P.; Smith, G. P.; Corno, A.; Bethge, L.; Klussmann, S.; Paraboschi, E. M.; Asselta, R.; Colombo, D.; Zanchetta, G.; Clark, N. A & Bellini, T. 
ACS Nano 12, 10, 9750-9762 (2018)

Backbone-free Watson Crick duplex-stacked nucleic acids
Smith, G. P.*; Fraccia, T. P.*; Todisco, M.; Zanchetta, G.; Zhu, C.; Hayden, E.; Bellini, T. & Clark, N. A. 
Proc. Natl. Acad. Sci. USA 115, 33, E7658 (2018)
*equally contributing authors
Article awarded with Cozzarelli Prize 2018

Liquid Crystal Ordering of 4-Base-Long DNA Oligomers with Both G-C and A-T Pairing
Fraccia, T. P.; Smith, G. P.; Clark, N. A & Bellini, T.
Crystals 8, 5 (2018)

Giant optical nonlinearity in DNA lyotropic liquid crystals
Lucchetti L.; Fraccia, T. P.; Ciciulla F.; Simoni F. & Bellini, T.
Optics Express 25, 25951 (2017)

Non-linear Optical Measurement of the Twist Elastic Constant in Thermotropic and DNA Lyotropic Chiral Nematics
Lucchetti L.; Fraccia, T. P.; Ciciulla F. & Bellini, T.
Scientific Reports 7, 4959 (2017)

Liquid Crystal Ordering and Isotropic Gelation in Solutions of 4-base-long DNA Oligomers
Fraccia, T. P.; Smith, G. P.; Bethge, L.; Zanchetta, G.; Nava, G.; Klussman, S.; Clark, N. A. & Bellini, T.
ACS Nano 10, 8508-8516 (2016)

Evidence of Liquid Crystal–Assisted Abiotic Ligation of Nucleic Acids
Fraccia, T. P.; Zanchetta, G.; Rimoldi, V.; Clark, N. A. & Bellini, T. 
Orig. Life Evol. Biosph. 45, 51–68 (2015)

Abiotic Ligation of DNA Oligomers Templated by Their Liquid Crystal Ordering
Fraccia, T. P.; Smith, G. P.; Zanchetta, G.; Paraboschi, E.; Yi, Y.; Walba, D. M.; Dieci, G.; Clark, N. A & Bellini, T. 
Nature Communications 6, 6424 (2015)

Liquid crystal self-assembly of random-sequence DNA oligomers
Bellini, T.; Zanchetta, G.; Fraccia, T. P.; Cerbino, R.; Tsai, E.; Smith, G. P.; Moran, M. J.; Walba, D. M. & Clark, N. A.
Proc. Natl. Acad. Sci. USA 109, 1110–1115 (2012)