Publications

Google Scholar listing.

* joint authorship


Transient compartmentalization of RNA replicators prevents extinction due to parasites.
Shigeyoshi Matsumura, Ádám Kun, Michael Ryckelynck, Faith Coldren, András Szilágyi, Fabrice Jossinet, Christian Rick, Philippe Nghe, Eörs Szathmáry, Andrew D Griffiths
Science (2016)

Generation and filtering of gene expression noise by the bacterial cell cycle.
Noreen Walker, Philippe Nghe, Sander J. Tans
BMC Biology (2016)
pdf

Individuality and universality in the growth-division laws of single E. coli cells
Andrew S. Kennard, Matteo Osella, Avelino Javer, Jacopo Grilli, Philippe Nghe, Sander J. Tans, Pietro Cicuta, and Marco Cosentino Lagomarsino
Physical Review E (2016)
pdf

Prebiotic network evolution: six key parameters
Philippe Nghe, Wim Hordijk, Stuart A Kauffman, Sara I Walker, Francis J Schmidt, Harry Kemble, Jessica AM Yeates, Niles Lehman
Molecular Biosystems (2015)
pdf

Stochasticity of metabolism and growth at the single-cell level
Daniel J Kiviet*, Philippe Nghe*, Noreen Walker, Sarah Boulineau, Vanda Sunderlikova, Sander J Tans
Nature (2014)
pdf

Metabolisme verloopt onregelmatig
Stochastic fluctuations in the expression of metabolic enzymes can destabilize growth and perturb the expression of any other gene.

Evolutionary constraints in variable environments, from proteins to networks
Katja M Taute*, Sebastian Gude*, Philippe Nghe*, Sander J Tans
Trends in Genetics (2014)
pdf

TIG
Genetic interactions, or epistasis, are modulated by the environment. This can create or relieve constraints on evolution at all levels of organization.

Microfabricated Polyacrylamide Devices for the Controlled Culture of Growing Cells and Developing Organisms
Philippe Nghe*, Sarah Boulineau*, Sebastian Gude, Pierre Recouvreux, Jeroen S van Zon, Sander J Tans
Plos One (2013)
pdf

acrylamide
Polyacrylamide gel pads can be very easily molded to obtain culture chambers for micro-organisms or multi-cellular organisms such as worms, to confine them and control their environment in space and time.

Single-cell dynamics reveals sustained growth during diauxic shifts
Sarah Boulineau, Filipe Tostevin, Daniel J Kiviet, Pieter Rein ten Wolde, Philippe Nghe, Sander J Tans
Plos One (2013)
pdf

diauxic
During the transition from glucose to lactose as a carbon souce, some bacteria do not show any lag phase due to prior stochastic expression of lactose metabolism enzymes.

Soft Matter Physics (2008 – 2011)

Microfluidics and complex fluids
Philippe Nghe, Emmanuel Terriac, Marc Schneider, ZhenZhen Li, Michel Cloitre, Benjamin Abecassis, Patrick Tabeling
Lab on a Chip (2011)
pdf

Flow-induced polymer degradation probed by a high throughput microfluidic set-up
Philippe Nghe, Patrick Tabeling, Armand Ajdari
Journal of Non-Newtonian Fluid Mechanics (2010)
pdf

Interfacially driven instability in the microchannel flow of a shear-banding fluid
Philippe Nghe, Suzanne M Fielding, Patrick Tabeling, Armand Ajdari
Physical review letters (2010)
pdf

High shear rheology of shear banding fluids in microchannels
Philippe Nghe, Guillaume Degré, Patrick Tabeling, Armand Ajdari
Applied Physics Letters (2008)
pdf

Microfluidic stickers
Denis Bartolo, Guillaume Degré, Philippe Nghe, Vincent Studer
Lab on a Chip (2008)
pdf


Laboratory of BioChemistry ESPCI Paris-Tech